My grandbaby is 4 months old and is devastated when she gets her shots.

This is the second time I went with my daughter to the doctor for support while my granddaughter gets her shots. She gets 4 of them every 2 months. My granddaughter is very good and hardly ever cries and smiles all the time, but when she gets the shots, she cries about it continuously all day and all we can do is hold her. When she tries to go to sleep she awakes screaming and we cannot put her down. She gets exhausted and even cries in her sleep. My daughter feels so hurt because she thinks that her baby thinks she did it to her. It takes about 2 days for her to get over it. We gave her the tylenol this time before we went to the doctor, but it did not seem to help. She did not want to take her bottle and she spit up alot. She just gets so devasted that it just breaks our hearts. Any suggestions, so that these shots will not be so painful?